Viagra is now considered that little magic pill for many men around the world. It’s the miracle medicine that helped them with a problem they found both embarrassing and difficult to treat. viagra apoteket utan recept isn’t magic though, it’s a drug with side-effects and contraindications which should be taken into consideration. Viagra or Sildenafil is a drug used in the treatment of erectile dysfunction. Erectile dysfunction is defined as failure to attain or maintain an erection sufficient for sexual intercourse. The penis passes through 2 stages during stimulation, a stage where the sympathetic systemic is dominant (the flaccid stage) and a stage where the parasympathetic system is dominant (the erection stage). During the parasympathetic stage, blood vessels dilate in the penis allowing blood flow to increase and cause an erection.
This dilatation of penile blood vessels is mediated by the release of nitric oxide from the lining of the blood vessel walls. Nitric oxide then reacts with an enzyme known as guanylate cyclase thus leading to the development of a substance called cGMP. This substance causes the relaxation of the smooth muscles in the blood vessel walls and thus their relaxation. The flaccid stage occurs when cGMP is degraded by the effect of an enzyme known as phosphodiesterase (PDE5). The role of Sildenafil or Viagra is to inhibit PDE5 activity and therefore it will prolong the survival of cGMP, subsequently prolonging the dilatation of the penile blood vessels and therefore helping to maintain an erection.
Still, what has Viagra got to do with blood pressure?
Well, technically Viagra causes blood vessel dilatation. In a patient with high blood pressure, a drug which causes vasodilatation and therefore increased blood flow used alone is not always the therapy of choice and may exacerbate the condition rather than improve it. Many anti-hypertensive drugs work to decrease blood pressure also, by dilating blood vessels. Therefore it would be assumed that the effect of both anti-hypertensive drugs and Viagra combined would cause a severe decrease in blood pressure. Actually, according to research, minor side effects such as faintness and dizziness may occur. Generally though, Viagra has been found to be a safe drug to use in hypertensive patients, even if combined with other vasodilators.
But is it really that common for a patient to be both hypertensive and suffering from erectile dysfunction? Actually, it’s much more common than people köpa cialis think. This is simply because hypertension maybe the underlying cause of erectile dysfunction. One of the major complications of hypertension after all, is the damage of vascular walls and since penile erection requires the integrity of blood vessels, the relationship seems completely logical. That is why erectile dysfunction should be a strong enough cause to suggest the presence of hypertension, especially if accompanied by other signs of hypertensive complications such as retinal damage and impairment of kidney function. Diagnostic tests should be performed to exclude hypertension as an underlying cause. Also, it is important for all patients taking both anti-hypertensive medication and Viagra to follow-up their blood pressure carefully in order to avoid the possibility of any complications that may occur.